Rhyothemis

Familial Mediterranean Fever: A Comprehensive Review of Pathogenesis, Genetics, and Epigenetic Regulation [2026]
https://pmc.ncbi.nlm.nih.gov/articles/PMC12758588

the bad news:
"Patients carrying identical MEFV variants, particularly those with low penetrance, may exhibit a wide spectrum of disease courses, ranging from subclinical carriers to severe, colchicine-resistant FMF."

the good news:
"For decades, researchers have sought to explain the high carrier frequency of FMF-associated variants among Mediterranean populations, interpreting it as a possible outcome of selective advantage against a historical disease. Y. pestis, the plague-causing bacterium, has emerged as a plausible driver of positive selection in FMF carriers ..."

#genetics #rheumatology #immunology #plague #InfectiousDiseases #FamilialMediterraneanFever #MEFV #FMF

Use of baking soda (sodium bicarbonate) to suppress allergic hypersensitivity reactions -
https://www.youtube.com/watch?v=LOnsjfECvr4&t=1984s

One of my main reactions is painful swallowing. I had an upper endoscopy to check for eosinophilic esophagitis but biopsies were normal - but I have the same symptoms as EoE. Pain is greatly reduced by drinking a baking soda solution.

I first tried baking soda after I noticed that my symptoms were worse if drinking something acidic (lemon water), and improved if I drank something basic (Oatly oatmilk). I had not seen the video or heard of the Japanese case report.

#MCAS #Allergies #CornAllergy

Using the body’s own sounds to diagnose Alzheimer’s and Parkinson’s before the first symptoms appear | Rachel Bouserhal
7 May 2026
https://theconversation.com/using-the-bodys-own-sounds-to-diagnose-alzheimers-and-parkinsons-before-the-first-symptoms-appear-279995

"For example, the ratio of inhalation to exhalation in people with Parkinson’s disease, or the interactions between breathing and swallowing, are altered very early on, long before symptoms become severe enough to be noticed. Similarly, the eye movements of patients with Alzheimer’s disease, particularly saccades, could be captured using an in-ear microphone and provide valuable information about the progression of the disease."

#Parkinsons #Alzheimers #medicine #health #aging #OcclusionEffect #Diagnostics

Anyone know what to make of this entry in Marker DB 2.0? Apparently it is unpublished data (not published in a journal article, though published in this entry) on threonic acid as a urinary biomarker in eosinophilic esophagitis -
https://markerdb.ca/chemicals/494

#EosinophilicEsophagitis

Shedding Light on FIRE Syndrome: An Overview of a Novel Condition in Eosinophilic Esophagitis [2025]
https://www.mdpi.com/2076-3417/15/11/6375

Like this redditor - I'm triggered by inhaling VOCs
https://www.reddit.com/r/EosinophilicE/comments/1cjbdld/fire_like_reaction_from_something_inhaled/

If I get exposed to VOCs, my reactivity to food increases - so not exactly like the OP on the reddit thread.

#EosinophilicEsophagitis #NEISVoid #AirPollution #EnvironmentalHealth

#Poople #423 5/5
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https://poople.io/

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Rev. Mariann Budde stepping down as Episcopal bishop of Washington | NBC4 Washington | NBC4 Washington
https://youtu.be/_W6WlyDoOGg

#news #USpol #religion

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https://poople.io/

COVID-19 Associated With Subsequent Asthma and Atopic Conditions | Colby Strong, Pulmonology Advisor
23 June 2026
https://www.pulmonologyadvisor.com/news/post-covid-19-onset-asthma-allergies-risk/

#Allergies #Asthma #Eczema #MCAS #HistamineIntolerance